(S)-2,3-Bis(tert-butoxycarbonyl)-2,3-diazabicyclo[3.1.1]heptane-4-carboxylic acid

Technical Details of (S)-2,3-Bis(tert-butoxycarbonyl)-2,3-diazabicyclo[3.1.1]heptane-4-carboxylic acid CAS No.3034241-44-3

CAS No3034241-44-3
Molecular Weight342.3874
Molecular StructureC16H26N2O6

Applications of (S)-2,3-Bis(tert-butoxycarbonyl)-2,3-diazabicyclo[3.1.1]heptane-4-carboxylic acid CAS No.3034241-44-3

In the field of KRAS drug discovery, it is primarily used as an advanced intermediate to synthesize "Next-Generation" inhibitors (RAS-ON inhibitors) that target multiple mutations, including KRAS G12D. Its role is closely associated with the development of drugs like RMC-9805 and other pipeline therapies from Revolution Medicines.


Features / Description of (S)-2,3-Bis(tert-butoxycarbonyl)-2,3-diazabicyclo[3.1.1]heptane-4-carboxylic acid CAS No.3034241-44-3

S)-2,3-Bis(tert-butoxycarbonyl)-2,3-diazabicyclo[3.1.1]heptane-4-carboxylic acid is a highly specialized, bridged bicyclic building block.